Histidine Benefits, Dosage, Deficiency, Sources

Histamine: It is amino imidazolepropionic acid and appears to be essential for growth, but not for the maintenance of nitrogen equilibrium. It is not synthesized in the body, but is synthesized in the micro-organism. The histidine, like arginine is nutrionally semiessential, as adult human can be maintained in nitrogen balance for short periods in the absence of histidine. The decarboxylation of histidine gives histamine. This is catalysed by aromatic amino acid decarboxylase, as well as enzyme histidine deccarboxylase present in most cells. The decarboxylase is inhibited by methyl amino acids, which this is used as antihypertensive agents. The histamine formation is concerned with initiating and sustaining rapid tissue growth. Histamine has important actions on the circulation, on smooth muscle, on secretions, and in producing itch or possibly pain. In circulation it produces arteriolar as well as precapillary sphincter dilatation. An injection of histamine causes fall of blood pressure and a rise of heart rate. Histamine increases the tone of most types of smooth muscle, e.g. intestine and bronchioles. Histamine stimulates salivary, pancreatic, intestinal, and pepsin secretions. When pricked into the skin, produce itching or pain due to stimulation of nerve endings. Histamine release in urticaria is associated with itching. The synthesis of histidine leads to formation of urocanic acid, glutamic acid, formic acid, and ammonia. An inherited defect in the enzyme histidase causes plasma levels of histidine to increase, and pyruvate and other histidine metabolites appear in the urine. A majority of patients are clinically normal, although abnormalities as mental retardation and speech defects may be seen. The enzyme deficiency is manifested in skin and liver biopsy specimens. Histidine compounds in the body include ergothioneine in red blood cells and liver. It is not synthesized in the body and comes purely from dietary source. Others are carnosine and anserine found in muscle, and give methylhistidine in urine. The genetic disorders for metabolism of histidine are: Imidazole amino aciduria; wherein large amounts of histidine and its above named compounds are excreted through urine together with a condtion of cerebromacular degeneration Histidinemia; it is due to hypoactivity of the enzyme histidase present in the liver causing retarded speech. It is essential for growth and the repair of human tissues. Its deficiency can cause joints pains, rheumatoid arthritis. It is beneficial in cardiovascular disorders as it dilates the blood vessels. It promotes sexual arousal, cures allergic conditions, and treats anaemia and auditory nerve disorders. It stimulates Hcl secretion in the stomach, and thus who have ulcers should avoid its intake. Sources of Histidine: Histidine is found in parboiled rice, barely, red gram dal, cow pea, moth beans, rajmah, spinach, drumstick leaves, radish, yam, green plantain, French beans, gingelly seeds, sunflower seeds, banana, grapes, beef, and cheese. The RDA is 10 mg per kg. of body weight. Read complete and updated information on amino acid, essential amino acid, amino acid supplement, 20 amino acid, amino acid structure, amino acid chain, amino acid protein, and amino acid food 24-Hour Processing - We handle and process Your deca durabolin or sustanon within 24.Competitive Prices - We offer some of the most competitive prices for deca durabolin, sustanon, dianabol... Extensive Customer Service - We offer comprehensive order support and customer service with full feedback and support throughout ordering and receiving.Special Prices And Discounts - We offer special prices and discounts for all large quantity purchases -see special offer section for favorites deca durabolin, sustanon, dianabol... discounts.Wide Range Product Assortment - We offer a wide-ranging product inventory that includes best sellers deca durabolin, sustanon, dianabol and winstrol. Designed to meet all Deca durabolin, sustanon, dianabol, anabolic steroids,dbol, deca,sustanon 250, anadrol,buy sustanon, buy deca durabolin, buy anadrol, buy winstrol, buy dianabol, buy deca, buy anabolic steroids, buy dbol, buy sustanon 250, buy anadrol, anavar, winstrol, winstrol depot, clenbuterol, cytomel, primobolan, primobolan depot, equipoise Your bodybuilding requirements. Deca Durabolin, Dianabol, Sustanon, Anadrol, Winstrol, ANABOLICS, Andriol, Arimidex, Primobolan, Clomid, Cytomel, Proviron, Testosterone, Anavar Visit us http://www.shrenksonlinepharma.com